Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms. The book primarily discusses classes of polymers and polymeric vehicles, including particulates, such as latexes, coacervates, ion-exchange resins, and liposomes, as well as non-particulate vehicles such as enteric coatings, mediators, and bioadhesives. Other topics discussed include diffusion; biodegradation-controlled delivery; animal model studies for toxicity, metabolism, and elimination testing; and FDA requirements for clinical studies. Drug delivery researchers will find this book to be an invaluable reference tool.
Table of Contents
1. Diffusion Controlled Systems: Polymeric Microcapsules 2. Diffusion Controlled Systems: Hydrogels 3. Polymers for Enteric Coating Applications 4. Coacervation: Principles and Applications 5. Polymerized Liposomes as Drug Carriers 6. Bioadhesive Polymers and Drug Delivery 7. Synthetic Bioerodible Polymer Drug Systems 8. Collagen-Based Drug Delivery Devices 9. Acrylic Latex Systems 10. Poloxamers in the Pharmaceutical Industry 11. Ion-Exchange Resin Delivery Systems 12. Animal Testing of Polymer Based Systems 13. Regulatory Requirements for New Drug Submissions 14. Beyond Today’s Technology
Tarcha, Peter J.